Social Impulsivity Inversely Associated with CSF 5-HIAA and Fluoxetine Exposure in Vervet Monkeys

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Csf 5 - Hiaa in Violent and Non-violent Suicide Attempters

Many studies have reported involvement of monoamine neurotransmission in suicide through measurement of serotonin and its main metabolite, 5-HIAA, in brain of suicide victims and in CSF of suicide attempters. 23 non-depressed non-psychotic suicide attempters and equal number of controls were selected, and all the subjects were screened on Cornell Medical Index. Suicide attempters were assessed ...

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Social Coordination: Patience Is a Virtue for Vervet Monkeys

Free-ranging vervet monkeys can solve a complex, multi-player coordination problem, learning to remain outside a 'forbidden circle' imposed by one member of the troop, in the absence of any social learning, communication, or policing by more dominant animals.

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Maternal absence and stability of individual differences in CSF 5-HIAA concentrations in rhesus monkey infants.

OBJECTIVE Early life events often lead to deficits in CNS serotonin function, which underlie a number of reoccurring psychopathological disorders. Studies using rhesus macaques have demonstrated that early maternal deprivation reduces CNS serotonin turnover, as measured by cisternal CSF 5-HIAA concentrations. In addition, individual differences in CSF 5-HIAA remain stable from the first year of...

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Hippocampal Neuron Populations Are Reduced in Vervet Monkeys With Fetal Alcohol Exposure

Prenatal exposure to beverage alcohol is a major cause of mild mental retardation and developmental delay. In nonendangered alcohol-preferring vervet monkeys, we modeled the most common nondysmorphic form of fetal alcohol syndrome disorder with voluntary drinking during the third trimester of pregnancy. Here, we report significant numerical reductions in the principal hippocampal neurons of fet...

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ژورنال

عنوان ژورنال: Neuropsychopharmacology

سال: 2001

ISSN: 0893-133X

DOI: 10.1016/s0893-133x(00)00211-6